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DeCS
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Descriptor Inglés:
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Pre-B Cell Receptors
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Descriptor Español:
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receptores de precursores de linfocitos B
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Descriptor Portugués:
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Receptores de Células Precursoras de Linfócitos B
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Sinónimos Inglés:
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Cell Receptor, Pre-B
Cell Receptors, Pre-B
Pre B Cell Receptor
Pre B Cell Receptors
Pre-B Cell Receptor
Receptor, Pre-B Cell
Receptors, Pre-B Cell
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Categoría:
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D12.776.124.790.651.950.750
D12.776.377.715.548.950.750
D12.776.543.750.705.816.821.750
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Definición Inglés:
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Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells. |
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Nota Histórica Inglés:
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2008
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Calificadores Permitidos Inglés:
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Número del Registro:
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52788
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Identificador Único:
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D054420
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Ocurrencia en la BVS:
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Similar:
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DeCS
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